Searchable abstracts of presentations at key conferences in endocrinology

ea0029p760 | Endocrine Disruptors | ICEECE2012

Unconjugated bisphenol A cord blood levels in boys with descended or undescended testes

Fenichel P. , Dechaux H. , Harthe C. , Ferrari P. , Pacini P. , Wagner-Mahler K. , Pugeat M. , Brucker-davis F.

Background: Human toxicity of bisphenol-A (BPA), a weak estrogenic environmental endocrine disruptor widely used in plastics, babybottles, cans and dental sealants, is under investigation. Human pharmacokinetics involves a rapid inactivation by hepatic glucuronyl- or sulfoconjugation and renal clearance. Fetal or perinatal exposure in rodents is associated with programmed adult reproductive diseases. Human epidemiological studies remain scarce especially concerning testicular ...

ea0029p57 | Adrenal cortex | ICEECE2012

Reevaluation of the 4 mg intravenous dexamethasone suppression test for differentiation of Cushing’s disease from pseudo-Cushing’s syndrome

Nouvel M. , Rabilloud M. , Raverot V. , Pignard C. , Vouillarmet J. , Thivolet C. , Jouanneau E. , Chazot F Borson , Pugeat M. , Raverot G.

Context: Differentiating Cushing’s disease (CD) from pseudo-Cushing’s syndrome (PCS) is one of the most challenging problems since no biological test is yet perfect. Almost 30 years ago our group demonstrated the interest of 4 mg i.v. dexamethasone suppressing test (DST) to differentiate obese patients to CD.Objective: To reevaluate the diagnostic accuracy of the 4 mg i.v. DST in carefully selected patients with PCS and CD.<p class="abstext...